Peer-Reviewed Study

Obstructive sleep apnea mouth breathing phenotype response to combination oral appliance therapy

Author(s): Preetam Schramm*, Emet Schneiderman, Jason Hui, Zohre German, William Stenberg and Ju Ying Lin
Published in Frontiers in Sleep.


Devices Used: myTAP

“Our data suggest oral appliance plus mouth shield use likely restored some processes of homeostatic neuromuscular
control, attenuated collapsibility and improved chemo-reflex dynamics (i.e. lower loop gain resulting in less oxygen saturation° change from baseline at T1 – 3 and decrease in supine respiratory rate) compared with oral appliance only. … Exploratory investigation showed within each group, persistent mouth breathing and snoring was present in those using at least one prescribed medication versus non-medication users. Furthermore, at T3, non-users had a lower
respiratory event index (6.4 events/h) compared with medication users (17.8 events/h) (Supplemental Table 2).”